diethylene glycol monobutyl ether toxicity

Synonyms Ethylene Glycol Monobutyl Ether, Butyl Cellosolve* 8 ETHYLENE GLYCOL ETHERS, NTP TOXICITY REPORT NUMBER 26 Glycol alkyl ethers represent a class of high-production-volume chemicals with widespread industrial applications as solvents and chemical intermediates. Evaluation of the subchronic toxicity of diethylene glycol monobutyl ether administered orally to rats [abstract]. Ethylene glycol monomethyl ether (EGME) and its acetate ester (EGMEA) are highly flammable, colorless, moderately volatile liquids with very good solubility properties. Serged and bound seams are degraded by some hazardous liquid chemicals, such as strong acids, and should not be worn when these chemicals are present. Because results were strongly suggestive of potential reproductive toxicity, a teratology study was conducted in Sprague-Dawley rats. Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Developmental & Reproductive Toxicity . Diethylene glycol butyl ether (2-(2-Butoxyethoxy)ethanol) is an organic compound, one of several glycol ether solvents. It is a colorless liquid with a low odour and high boiling point. Diethylene glycol monobutyl ether was obtained from Union Carbide Chemical Co. as Butyl Carbitol, Lot #S767216. Liquide transparent, incolore à odeur caractéristique. EPA reviewed the available human health toxicity data and aquatic ecological toxicity data for EGBE and concluded that it can reasonably be anticipated to cause serious or … EPA/OTS Doc #: 86-890001170S. The site is secure. It is a colorless, practically odorless, poisonous, and hygroscopic liquid with a sweetish taste. Toshihiro Kawamoto 1, Koji Matsuno 1, Fujio Kayama 1, Manabu Hirai 2, Kelichi Arashidani 2, Masahiro Yoshikawa 2 & Yasushi Kodama 1 Bulletin of Environmental Contamination and Toxicology volume 44, pages 602 – 608 (1990)Cite this article. The subchronic and reproductive toxicity of diethylene glycol butyl ether (DGBE) by the dermal route was evaluated in Sprague-Dawley rats using a novel combined protocol. DGBE was administered dermally at 10 or 30% v/v in aqueous solutions or undiluted (100%) for 13 weeks under occlusion, 6 hr/day, 5 days/week at a maximum attainable volume of 2 mL/kg. Liquide hygroscopique, incolore à odeur fruitée. … Diethylene glycol (DEG) is an organic compound with the formula (HOCH 2 CH 2) 2 O. Mise à jour : 1994-03-24. Objectives The solvent, dimethylene glycol monobutyl ether (DGBE), is a component of latex paints, inks; it is used as a degreasing agent, industrial detergent. Propriétés physiques 1. The aim of the study was evaluating the effects of DGBE administered by gavage on the estrous cycle and given with drinking water on fertility in rats and early development of their progeny. Author information: (1)Department of Toxicology and Environmental Research and Consulting, The Dow Chemical Company, Midland, MI 48674, USA. Glycol is a chemical compound that is diol containing two hydroxyl groups. The difference between ethylene glycol and diethylene glycol is that an ethylene glycol molecule is an individual molecule whereas diethylene glycol molecule is formed by the combination of two ethylene glycol molecules via an ether bond. DEG is a widely used solvent. Toxicologist 1986;6:659. This website and underlying databases are maintained and updated by Pesticide Action Network North America (PAN). Comparative toxicity studies with three glycol ethers, 2-methoxyethanol, 2-ethoxyethanol, and 2-butoxyethanol, … Diethylene glycol monobutyl ether for synthesis Synonym: Butyl carbitol, 2-(2-Butoxyethoxy) ethanol, Butyl diglycol, Diethylene glycol monobutyl ether CAS Number 112-34-5. Couleur / Aspect: incolore: Odeur: caractéristique: Densité : 0,955: Point Eclair: 105°C: Point d'ébullition: 230°C: N° CAS: 112-34-5: À voir également. Linear Formula HOCH 2 CH 2 OCH 2 CH 2 O(CH 2) 3 CH 3. Superlist … … 2-(2-Butoxyethoxy)ethyl acetate. In response to a USEPA TSCA Test Rule, a series of toxicity studies were conducted in the early 1990’s. Solvant de produits organiques, fabrication de produits organiques. Testing Status of Diethylene glycol monobutyl ether 11139-J . 2,2'-OXYBIS- ETHANOL, 2,2'-OXYBISETHANOL, 2,2'-OXYDIETHANOL, BIS(2-HYDROXYETHYL)ETHER, DIETHYLENE GLYCOL, DIGLYCOL, ETHANOL, 2,2 OXYBIS, and ETHANOL, 2,2'-OXYBIS-Cancer . The available information on the acute and subchronic toxicity of ethylene glycol monobutyl ether is reviewed. Three additional structural analogs are included to support this category. Diethylene glycol monobutyl ether agent detailed information in Haz-Map database. (Concise international chemical assessment document ; 41) 1.Ethylene glycols - adverse effects 2.Ethylene glycols - toxicity 3.Methyl ethers - adverse effects 4.Methyl ethers - toxicity 5.Risk assessment 6.Environmental exposure I.International Programme on Chemical Safety II.Series Diethylene glycol hexyl ether is not expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(4). EINECS 204-685-9. Systematic Names. Both ethylene glycol and diethylene glycol are produced from same starting material; ethylene. Diethylene glycol monobutyl ether (DGBE) has not been as extensively studied as EGBE; however, the available toxicity studies have been reviewed (Gingell et al., 1996, Boatman and Knaak, 2001). A preliminary toxicity assay was performed with strain … Diethylene glycol dimethyl ether. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. kajohnson@dow.com Standard toxicologic endpoints, supplemented by … Diethylene Glycol Monobutyl Ether (>95%) 112-34-5: Liquid >480 > indicates greater than. Furthermore, it is listed in section II, perfume and aromatic raw materials. 3.9 Chronic Toxicity: Currently not available 3.10 Vapor (Gas) ... DIETHYLENE GLYCOL MONOBUTYL ETHER DME 9.20 SATURATED LIQUID DENSITY Temperature (degrees F) Pounds per cubic foot 35 40 45 50 55 60 65 70 75 80 85 90 95 100 60.410 60.280 60.150 60.020 59.890 59.760 59.630 59.500 59.370 59.240 59.110 58.980 58.850 … Mise à jour : 2009-08-19. Diethylene glycol monomethyl ether (diEGME) was one of 15 glycols tested in CD-1 mice using a short-term in vivo reproductive toxicity assay (Chernoff/Kavlock test). Dipropylene glycol monomethyl ether DPM (CAS 34590-94-8) - Éther de dipropylène glycol monométhylique. UNII-U6UTS77LXB. Diethylene glycol monobutyl ether; Utilisation et sources d'émission. Johnson KA(1), Baker PC, Kan HL, Maurissen JP, Spencer PJ, Marty MS. Production and Use. Diethylene glycol monobutyl ether (DGBE): two- and thirteen-week oral toxicity studies in Fischer 344 rats. Johnson KA, Baker PC, Kan HL, Maurissen JP, Spencer PJ, Marty MS. Diethylene glycol monobutyl ether (DGBE): two and thirteen-week oral toxicity studies in Fisher 344 rats. Acute oral toxicity of ethylene glycol monomethyl ether and diethylene glycol monomethyl ether. 79 Accesses. Diethylene glycol monobutyl ether. Biodegradation of diethylene glycol hexyl ether may take place based on a study using pure culture Pseudomonas sp 4-5-3 which degraded diethylene glycol hexyl ether … It can also serve as a dispersant in organosols and can also be used in preparation of plasticizers. Each of them has previously been endorsed at a SIAM. Salmonella (401459) Completed . 3 Altmetric. Packaging 1, 4 L in poly bottle 18 L in steel drum Legal Information Product of Dow Chemical Diethylene glycol monoethyl ether; Utilisation et sources d'émission . The fabric may or may not offer barrier. NTIS/OTS0520310. 14. In a clinical setting, most commonly encountered glycol is ethylene glycol. It is miscible in water, alcohol, ether, acetone, and ethylene glycol. Diethylene glycol, monobutyl ether, acetate. OF DIETHYLENE GLYCOL MONOBUTYL ETHER (DGBE) IN RATS KRYSTYNA SITAREK, JOLANTA GROMADZIŃSKA, PIOTR LUTZ, JAN STETKIEWICZ, RADOSŁAW ŚWIERCZ, and WOJCIECH WĄSOWICZ Nofer Institute of Occupational Medicine, Łódź, Poland Department of Toxicology and Carcinogenesis Abstract Objectives: The solvent, dimethylene glycol monobutyl ether (DGBE), is a … Glycol ether DB aceatate . CASRN: 112-34-5 Formula: C8-H18-O3 Synonyms/Common Names. Footnote 11. Other less frequently encountered glycols include diethylene glycol, propylene glycol, ethylene glycol monobutyl ether (EGBE), and ethylene glycol monomethyl ether (EGME). Grand choix parmi 10 Kit complet béton ciré Mise à jour : 2009-08-19. Propriétés physiques 1 2. Mise à jour : 2003-06-06. Diethyleneglycol monobutyl ether acetate. A blank cell indicates the fabric has not been tested. Livraison rapide partout en France. Diethylene Glycol is an aliphatic diol. NSC 5175. In July 2007 the Spanish authorities informed the Commission services about their findings of DEG in concentrations as high as 7-8.3% in toothpaste products. EPA has denied a petition to remove Ethylene Glycol Monobutyl Ether (EGBE) from the list of chemicals subject to reporting under section 313 of the Emergency Planning and Community Right-to-Know Act (EPCRA). (1). 3.8 Toxicity by Inhalation: Currently not available. DGME is also used as a deicer … EC 204-685-9. Data from animal studies have been examined from the standpoint of dose-response relationships and the sensitivity of various animal species, including man, to the effects of this chemical. However, for aquatic toxicity, diethylene glycol ethers (DGEE, DGPE and DGHE) and diethylene glycol ether acetates (DGEEA and DGBEA) are considered separately because diethylene glycol ether acetates do not hydrolyze readily in water at environmental conditions. Dow Chem Co (1983) Dermal Teratology Method Development Study in Rabbits Using Diethylene Glycol Monomethyl Ether (sanitized). Special Warnings from DuPont. Ethanol, 2-(2-butoxyethoxy)-, 1-acetate. 106 THOMPSON ET AL. These studies included absorption and elimination of dermally applied doses Molecular Weight 162.23 . Hygiène et sécurité Apparence 1. Return to footnote 10 referrer. Diethylene glycol butyl ether is a high boiling solvent, which can be used in coating industry. MDL number MFCD00002881. 9 Citations. Diglycol monobutyl ether acetate. Salmonella Mutagenicity Test The plate incorporation mutagenicity assay with and without an Aroclor-induced Sprague-Dawley rat liver S-9 fraction was performed as described by Ames et al. … Food Chem Toxicol 2005;43:467–481. It is mainly used as a solvent for paints and varnishes in the chemical industry, household detergents, brewing chemicals and textile processing. Diethylene glycol monomethyl ether - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information: Note: See Working with the Information on this Page section below for important notes about this data. Caractéristiques. Google Scholar. HSDB 334. EC Index Number 203-961-6 Ethanol, 2-(2-butoxyethoxy)-, acetate. Provisional Peer-Reviewed Toxicity Values for Diethylene Glycol Monomethyl Ether (CASRN 111-77-3) ... Diethylene glycol monomethyl ether (DGME), also known by the International Union of Pure and Applied Chemistry (IUPAC) name of 2-(2-methoxyethoxy)ethanol, CASRN 111-77-3, is a solvent used in paints, printing inks, nitrocellulose resins, waxes, and dyes. diethylene glycol monobutyl ether ethanol diethylene glycol dimethyl ether triethylene glycol dimethyl ether propylene glycol monomethyl ether propylene glycol monomethyl ether acetate dipropylene glycol dipropylene glycol monomethyl ether A. bbreviation EGME EGMEA EGEE EGEEA EGPE EGBE EGDME EGDEE DEG DEGME DEGE DEGBE DEGDME TEGDME PGME PGMEA … Fabrication de produits organiques, solvant de produits organiques Hygiène et sécurité Apparence . EN STOCK : BUTYL DIGLYCOL Solvant diethylene glycol monobutyl ether - CAS N° 112-34-5 - Fût de 200L pas cher. Acute and Subchronic Toxicity of Ethylene Glycol Monobutyl Ether by Tipton R. Tyler* The available information on the acute and subchronic toxicity of ethylene glycol monobutyl ether is reviewed. 2-(2-Butoxyethoxy)ethanol ; Genetic Toxicology. Ektasolve DB acetate. Diethylene glycol (DEG) (CAS 111-46-6) is listed in the Inventory with functions as solvent, viscosity controlling and masking/perfuming. Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments. DPM Solvant dipropylene glycol monomethyl ether - CAS N° 34590-94-8. Satellite groups of male and female … Are maintained and updated by Pesticide Action Network North America ( PAN ) administered orally to rats [ ]... Liquid with a low odour and high boiling solvent, which can be used in preparation of plasticizers,! Complet béton ciré diethylene glycol monobutyl ether was obtained from Union Carbide Chemical Co. as Carbitol. Grand choix parmi 10 Kit complet béton ciré diethylene glycol monobutyl ether ( > 95 )! 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